1,4-DICHLOROBENZENEAuthor: Pacific Northwest Inspections Group, LLC Date: 25-Nov-2013. Category: Mold Add to Favorites
1,4-Dichlorobenzene (p-DCB, para-dichlorobenzene) is an organic compound with the formula C6H4Cl2. This colorless solid has a strong odor. In terms of its structure, the molecule consists of two chlorine atoms substituted for hydrogen at opposing sites on a benzene ring. p-DCB is used a pesticide and a deodorant, most familiarly in mothballs in which it is a replacement for the more traditional naphthalene. p-DCB is also used as a precursor in the production of the polymer poly(p-phenylene sulfide).
Human Health Effects:
Evidence for Carcinogenicity:
Cancer Classification: Group C Possible Human Carcinogen
Evaluation: There is inadequate evidence in humans for the carcinogenicity of dichlorobenzenes. ... There is sufficient evidence in experimental animals for the carcinogenicity of para-dichlorobenzene. Overall evaluation: In making the overall evaluation of the carcinogenicity of para-dichlorobenzene to humans, the Working Group concluded that para-dichlorobenzene produces renal tubular tumors in male rats by a non-DNA reactive mechanism, through an alpha-2u-globulin associated response. Therefore, the mechanism by which para-dichlorobenzene incr the incidences of renal tubular tumors in male rats is not relevant to humans. para-Dichlorobenzene caused a high incidence of liver tumors in male and female mice. Supporting evidence that its mechanism of action of carcinogenesis may be relevant for humans includes evidence that it causes DNA damage in liver and spleen of mice and weakly binds to DNA in mouse liver. ... para-Dichlorobenzene is possibly carcinogenic to humans (Group 2B).
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This chemical marker shows up 1 in 500 Residential VOC test and is very rare at levels above 2.